Posterior Reversible Encephalopathy Syndrome in a Young Sudanese Female - Case Report

Abstract

Introduction:

Posterior reversible encephalopathy syndrome (PRES) is a rare, reversible radio-neurological condition. It commonly presents with seizures, visual disturbances, headaches, impaired level of consciousness, and other focal neurological findings. PRES is often associated with high blood pressure and can result from various causes, including autoimmune disorders, certain medications, and eclampsia. Pathophysiologically, it is characterized by reversible vasogenic cerebral edema predominantly in the occipital and parietal lobes. We report a case of a young Sudanese female with systemic lupus erythematosus (SLE), presenting with generalized seizures and headache. These symptoms occurred without fever and were associated with high blood pressure. Neuro- radiological imaging findings, typical clinical presentation, and the reversibility of the condition confirmed the diagnosis of PRES. This is, to the best of our knowledge, the first case report of PRES in SLE patients from El Obeid, North Kordofan, Western Sudan